Which of the following substances is classified as a Schedule II drug?

Methadone is classified as a Schedule II drug due to its high potential for abuse, which can lead to severe psychological or physical dependence. Schedule II substances are considered to have legitimate medical uses but are tightly regulated because of the risks associated with their misuse. Methadone is primarily used in the treatment of opioid addiction and for pain management.

In contrast, hydrocodone with acetaminophen is often classified as a Schedule III drug when combined with other non-narcotic analgesics, indicating a lower potential for abuse compared to Schedule II substances. Dronabinol (Marinol) is a Schedule III drug as well, primarily used for nausea and to stimulate appetite in certain patient populations. Codeine with acetaminophen, commonly known as Tylenol No. 3, is classified as a Schedule III drug, signifying it has lower abuse potential than Schedule II drugs.

Understanding the classification system of controlled substances is crucial for ensuring their safe and effective use while minimizing the risk of abuse and dependency.