Which of the following has the highest potential for abuse?

Percocet is the correct answer because it contains a combination of oxycodone, an opioid analgesic, and acetaminophen. Oxycodone is classified as a Schedule II controlled substance due to its high potential for abuse, which can lead to severe psychological or physical dependence. The opioid properties of oxycodone contribute to its high abuse potential, particularly in individuals seeking pain relief, leading to misuse and addiction.

In comparison, while Percodan also contains oxycodone, it includes aspirin instead of acetaminophen, which could impact its usage patterns but does not necessarily contribute to a higher abuse potential than Percocet. Vicoprofen, which combines hydrocodone with ibuprofen, is also a Schedule II drug, but hydrocodone generally has a slightly lower abuse potential compared to oxycodone. Ativan, which contains lorazepam, is a benzodiazepine categorized as Schedule IV. Though it sedates and can lead to dependency, its potential for abuse is lower than that of Schedule II substances like oxycodone. Thus, among the choices listed, Percocet stands out due to the potency of its active ingredient, oxycodone.