What do the middle four digits of an NDC number indicate?

The middle four digits of a National Drug Code (NDC) number specifically indicate the drug's product code, which identifies the specific formulation, strength, and dosage form of the drug. This product code is crucial for distinguishing different products that may be marketed by various manufacturers.

In the context of the NDC, the first segment, consisting of five digits, typically identifies the manufacturer, while the last segment, consisting of two or more digits, provides details about the packaging, such as the package size and type. Therefore, understanding that the middle four digits are concerned with the specifics of the drug itself—its formulation and strength—helps clarify why that portion of the NDC is essential for identifying and differentiating pharmaceutical products in the market.

This structured format of the NDC allows for accurate tracking and regulation of pharmaceuticals, vitally important in pharmacy practice, ensuring safety and efficacy in medication dispensing and usage.