The second set of numbers in an NDC number refers to which aspect?

The second set of numbers in a National Drug Code (NDC) identifies the specific drug or formulation. The NDC is structured as a unique numeric identifier consisting of three segments: the first segment indicates the labeler or manufacturer, the second segment specifies the exact drug or formulation, and the third segment denotes the package size and type.

Understanding this structure is vital for pharmacy practice, as it helps in accurately identifying and verifying medications, supporting the safe dispensation of prescriptions. This specificity allows healthcare professionals to differentiate between drugs that may have similar names or active ingredients but differ in dosage forms, strengths, or formulations, thus ensuring patient safety.